Most notably with modified live canine distemper vaccination has induced disease In nondomestic species, species. The occurrence of such adverse events underscores the importance of developing appropriate vaccination protocols for nondomestic species.
The current Association of Zoos and Aquari. ums (AZA) Canid Taxon Advisory Group's(TAG) recommendation for vaccination of large canids does not specify the frequency of administration of multivalent combination vaccine These guidelines recommend that large canid pups receive vaccinations protecting against parvovirus and distemper administered beginning at 6-9 wk of age with boosters every 2-3 wk through 16-20 wk of age: however, the frequency of administration after the animal is 1 yr of age is not defined. Historically, Point Defiance Zoo and Aquarium (PDZA), site of the largest population of captive red wolves, has vaccinated red wolves (Canis rufus) on an annual basis for CDV and canine parvovirus and (CPV). with occasional vaccination against canine adenovirus (CAV) if multivalent vaccines were utilized. A previous study on red wolf response to vaccination for CPV and CDV indicated that this species could mount an immune response to vaccination with an antici pated duration greater than 1 yr This study single-agent, modified live vaccine(CDV and CPV) for red wolves using serologic data over a 3-4 yr interval. Serologic response to vaccination with CAV is also included.