preventing sufficient oxygen access to where it is needed
together with mitochondria inability to generate enough adenosine
triphosphate to maintain normal cellular function [11].
P. berghei parasite is used in predicting treatment outcomes of
any suspected antimalarial agent due to its high sensitivity to
chloroquine, making it the appropriate parasite for this study
[12]. In this study, three doses of the aqueous and D/M stem
bark extracts of H. barteri exerted curative antimalarial
activities against the blood stage of P. berghei. This implies
that the active principles for the observed antimalarial effects
are present in both the aqueous and D/M fractions. It is
proposed that the presence of alkaloids, tannins, triterpenoids