Our search strategy in PubMED yielded 97 articles for consideration in this review. Studies were excluded because the intervention studied was not omega-3 fatty acids (n=46), research was not performed in humans (n=7), the design was not a randomized controlled trial (n=6)or subjects were psychiatrically healthy (n=12). Additional randomized controlled trials examining the efficacy of omega-3 fatty acids for psychiatric conditions were excluded because subjects had bipolar disorder, obsessive-compulsive disorder, recurrent selfharm,borderline personality disorder, Alzheimer's disease, or because the trial did not include a placebo control group, examined pediatric depression, or involved starting concomitant antidepressant medications at the same time as starting omega-3 supplementation.