Analysis of the Vmax/Km ratio revealed that all mutants demonstrated 0.85- to 1.05-fold differences from the wild type, with the exception of variant CYP2A6*22, which only portrayed 39% of the wild-type intrinsic clearance.
Analysis of the Vmax/Km ratio revealed that all mutants demonstrated 0.85- to 1.05-fold differences from the wild type,with the exception of variant CYP2A6*22, which only portrayed 39% of the wild-type intrinsic clearance.