Sandfly fever (SF) is one of the emerging arboviral diseases
caused by sandfly fever viruses, which are transmitted to
humans by the bite of phlebotomine sandflies. The disease
is a self-limited febrile illness, and presents as a rapid onset
of high fever, severe myalgia and arthralgia, headache, and
in some cases photophobia, abdominal discomfort and
nausea.
An elevation in aminotransferases may be encountered
during the course of the disease, but extremely high levels
have been reported rarely. Herein, we report a diagnostic
challenge with sandfly fever who presented with very high
levels of aminotransferases and with the clinical and laboratory findings of typical acute viral hepatitis, which
caused diagnostic confusion with the classical hepatotropic
viruses.
A 33-year-old female was admitted to the emergency
service with fever malaise, anorexia, nausea, vomiting, and