4. ConclusionsThe results of this research indicate the possibility of using a het-erogeneous biocatalyst based encapsulated methylotrophic yeastOgataea polymorpha BKM Y-2559 in the sol-gel matrix as a sta-tionary phase in the column type biofilter for purifying methanolcontaining wastewater. Organo-silica shells covering yeast cellseffectively protect them from exposure to harmful factors, includ-ing extreme values of pH. Designed heterogeneous biocatalystcan effectively oxidize methyl alcohol under strongly alkaline orstrongly acidic conditions. The productivity of the biofilter based onencapsulated yeast cells is three times higher than the productivityof the aeration tanks at the methanol production plants. Further-more, the use of methylotrophic yeast as a biocatalyst allows formethanol containing wastewater purification with methyl alcoholconcentration up to 30 mmol/dm3. This may lead to the devel-opment of new and effective industrial wastewater treatmenttechnologies.