AF also significantly suppressed the multiplication of mouse lung fibroblast (L-929) cells at a concentration of 8 t~g/ml in long term culture. Oral administration of the extracts (CE and AF) retarded the development of solid and ascites tumours and increased the life span of these tumour bearing mice. Tritiated thymidine, uridine and leucine incorporation assay suggest that
the fraction acts directly on DNA synthesis.