Banking
The first nationally chartered bank in the United States, the Bank of North America, was founded in 1781 in Philadelphia. After a series of mergers, the Bank of North America is part of Wells Fargo, which uses national charter 1.
Pennsylvania is also the home to the first nationally chartered bank under the 1863 National Banking Act. That year, the Pittsburgh Savings & Trust Company received a national charter and renamed itself the First National Bank of Pittsburgh as part of the National Banking Act. That bank is still in existence today as PNC Financial Services, and remains based in Pittsburgh. PNC is the state's largest bank, and the sixth-largest in the United States.