The Region panel lists critical information concerning the region in which your city is located:
Minor Faction: each region hosts a Minor Faction whose villages you will find as you
explore. You have several options to Pacify a Minor Faction (by force, a bribe or
cooperation). Once this is done, you have the ability to Assimilate it. Until then, Minor
Faction villages can be a threat and generate hostile armies.
Luxury and Strategic Resources: The region can host deposits of these critical resources.
They will generate value once you have constructed the requisite extractor on site.
Strategic Resources are critical to equip your heroes and units with powerful items; Luxury
Resources allow you to give temporary boosts to your empire. At the beginning of the
game most Luxury and Strategic Resources are hidden, and must be unlocked through
technologies and sciences in new Research Eras
Trade routes are automatic exchanges made between series of connected cities (allies,
friends and yours), leading to FIDS bonuses on Cities: those creating routes and those
crossed by them.