The inset TEM image depicts that each fiber
took on a rough surface structure. Their average di-
ameter was found to be 500 nm. Moreover, as shown in
low magnification Fig. 1c, the self-supporting mat made
of HA nanofibers showed non-woven cloth-like char-
acteristic which should be particularly useful in modi-
fying surface features for site specific delivery like drug,
protein, polypeptides or gene.