Reduced Neurogenesis in Abx-Treated Mice Can Be Restored by Exercise and Probiotic Treatment
(A) The first panel shows representative micrographs of the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. Proliferating cells labeled with BrdU (red) arise in the SGZ of the DG, mature, and integrate into the granular cell layer labeled with NeuN (blue). Doublecortin (Dcx, green) is a marker for mitotic neuronal progenitor cells (NPCs) and NeuN (blue) is a marker for mature neurons (∗cell expressing BrdU and NeuN and #cell expressing BrdU/NeuN and Dcx).