Twelve of the females were taking contraceptives. All females were tested negaIrradiated Nonirradiated Fig. 1. Arrangement of test areas on the left and right sides of the back. Reuter /Jocher /Stump /Grossjohann / Franke /Schempp 108 Skin Pharmacol Physiol 2008;21:106–110 tive for pregnancy. All subjects completed the study according to the protocol. The MED of the 40 subjects ranged between 50 and 125 mJ/cm 2 ( fig. 2 ).