No studies have assessed change in troponin levels for
prediction of outcomes in a broad population of patients
with CHD who are clinically stable following myocardial
infarction (MI) or unstable angina. We therefore measured
troponin I (TnI) levels using a contemporary sensitive assay
(5) at baseline and their change at 1 year in patients in the
large LIPID (Long-Term Intervention with Pravastatin in
Ischaemic Disease) study and evaluated their relationship to
outcomes over long-term follow-up (6)