some groups found TNP to have
an effect on cellular inflammation
. TNP therapy imposes equally distributed
mechanical forces across
the wound
. mechanical stress has direct
effects on cellular activity and in
particular angiogenesis
Skin Foam/wound
interface
Wound bed
V.A.C.®
PU Foam
Compressive loading
Wound bed
Islands of
granulation
Tensile
loading
Figure 4. Topical negative pressure stimulates granulation
tissue formation.
Topical negative pressure therapy
Blackwell