Honey locust gum:
It is known botanically as Gleditsia triacanthos, and belongs
to the order Leguminosea (suborder Mimoseae). The gum is
obtained from the seeds of the plant. The seed contains
54 proteins, fats, carbohydrates and fibers .
Honey locust gum (HLG) was used to produce matrix tablets
at different concentrations (5% and 10%) by wet granulation
55 method . Theophylline was chosen as a model drug. The
matrix tablets containing hydroxyethylcellulose and
hydroxypropyl methylcellulose as sustaining polymers at the
same concentrations were prepared and a commercial
sustained release (CSR) tablet containing 200 mg
theophylline was examined for HLG performance. No
significant difference in in-vitro studies was found between
CSR tablet and the matrix tablet containing 10% HLG.