Fig. 8. Decreased mitochondrial zinc uptake in cancerous cell lines. RWPE-1,
RWPE-2, and PC-3 prostate cell lines were incubated for 24 h in medium
supplemented with (+) and without (−) 50 μM ZnCl2. RWPE-1 is the only cell
line demonstrating a statistically significant (P < 0.001) increase in mitochondrial
zinc uptake when incubated in zinc-enriched media.