Further experiments culturing Mycoleptodiscus sp. F0194 in PDA resulted in the isolation and characterization of several well-known antibacterial and cytotoxic compounds, such as verticillin B, melinacidin IV, and verticillin C.These latter metabolites are all epipolythiodioxopiperazines (ETPs), toxic secondary metabolites that are known to be made only by fungi They are characterized by the presence of an internal
disulfide bridge and an indole ring.