The ultrastructural quality of the material should permit observation of the
nuclear membrane and nuclear pores with preservation of chromatin structure
and nucleolar morphology in normal cells in the same material
(Figures 9.1 to 9.4). It is of the utmost importance to have comparison to
normal cells of the same category either in the same animal or in control
animals. Figure 9.1 shows a large pyramidal neuron in the cerebral cortex
with normal nuclear and cytoplasmic morphology. This animal was exposed
to a sham intoxication in a study of delayed neuronal degeneration in carbon
monoxide exposure.
13
In Table 9.1, a list of nuclear