Methods
Study population
A study cohort of 32 adults (6 women and 26 men) with
clinically established CAD were recruited from communities
in the Lower Naugatuck Valley, CT (an area with a
predominantly white population), through newspaper
advertisements and posters at frequented sites. Coronary
artery disease was defined by the presence of at least 1
coronary artery stenosis N50% determined angiographically
or through a documented history of ischemic heart
disease. The study population included men older than 35
years, postmenopausal women not on hormone replacement
therapy, and nonsmokers.