Musa sapientum Linn (Musaceae) commonly called 'Kela' in Hindi (English: Banana) is extensively cultivated throughout India. Till date different parts of Musa sapientum have been studied for anti ulcerogenic, hypoglycemic, hypolipidemic, antimicrobial, antihypertensive, wound healing, antacid, diuretic and antiestrogenic activities .The pill extract of banana was found to have analgesic property. But, there is no evidence in literature for analgesic activity of stem of Musa sapientum. Hence the present investigation was undertaken to study analgesic activity of aqueous (AMS) and ethanolic (EMS) extract of stem of Musa sapientum Linn. using hot plate method and tail immersion method. AMS and EMS (100mg/kg and 200mg/kg, i.p) significantly increased reaction time as compared to vehicle treated group. Maximum analgesic effect was observed at 30 min. interval for 100 mg/kg and 200 mg/kg, i.p. (P = 0.01). The present study indicates that AMS & EMS have central analgesic action