The other objectives are to determine the temperature-time data for pasteurization of the functional drink as well as to examine the in vitro bioavailability of hydrolyzed collagen in CJD. 2. Materials and methods 2.1. Materials The hydrolyzed collagen (Peptan™, F/2000 Da) enzymatically derived from fish was provided by Rousselot (2011) SAS, a Vion Company (Puteaux, France).