Yokomizo is a capable police officer, though with one odious personal habit: he tends to get his face right into a suspect's face, study them closely, and scream into their face when he believes he is onto something, a habit which even he believes is a little embarrassing. Another trait of his is to speak really loudly when deeply involved in an investigation. His loud voice has received many complaints from suspects.[6]
Sango considers him a big fan of Kogoro Mouri's work.[7] Often when he sees Kogoro, his demeanor changes and he has him help him investigate a case.[8] Sometimes, he even actually calls Kogoro and asks him to come with him, because there is a case that he is having a problem solving.[9] Kogoro however, sometimes puts down Sango's theories, even when it turns out Sango's intuitions are indeed the correct ones.[5] Kogoro does not always react the same way to seeing Sango, as Sango does to him,[10] but he does appear to consider Sango a good friend.
Inspector Yokomizo interrogates a suspect, using his usual menacing method.
Sango always acts very excited when he sees that Kogoro becomes "The Sleeping Kogoro".[11] However, Sango is more modest than Kogoro, as compared to Kogoro, who acts very excited and perverted.[12] Sango often mistakes female suspects or witnesses for Kogoro's wife.
Although he can be a menancing figure, he is shown to be a very adept inspector. He is shown in his first appearance on the show to realize who the killer is, and he is also the only one other than Conan to doubt the suspect's alibi, right down to the photographic trick the killer used to solidify their alibi.[7] Conan even has Sango look at the evidence Conan has found, to accuse the killer of the murder.[7] Conan also believes that Sango is a very adept and smart inspector, commenting during a case that Sango, who was the one in charge, would be a much smarter choice for figuring out the case over Kogoro Mouri.[13] In another case, he is the only adult to believe that a murder took place instead of a suicide at a temple, but Conan, when voicing Kogoro, still chides him for not paying attention to the obvious clues Sango had found.[8] Sango also has a big fear of ghosts, an even bigger fear of them than even Ran Mouri.[6]
He also has a softer side, like when he is shown with Professor Agasa and Conan Edogawa trying to comfort Ai Haibara after she breaks down to Conan, asking him why he didn't save her sister, Akemi Miyano.[14] He later on comes to think of Kogoro, Ran, and Conan as friends, often running to them and talking to them before anyone else if they appear at a murder case that he is investigating.[13] Sango sometimes contacts his brother, Jugo, whenever he needs help on a suspect in a case.[6] In one episode, Jugo helps out Sango by dressing up exactly like him, to help Conan in solving a murder.[6] However, Jugo does this very reluctantly, and even tells Sango to not mention that he helped out.[6]
Unlike most other characters, Sango does not mind Conan involving himself in cases. In fact, Sango often values Conan's opinion, as well as his keen observations, often asking him if he has found any clues, much to the chagrin of Kogoro.[15] Whenever Conan makes a point, or points out a clue, Kogoro immediately disregards it, while Sango is the only one who listens to Conan's points without acting in anger towards him, even taking his concerns seriously.[11] It is hinted that Sango also understands the Conan is no ordinary seven-year-old boy, and very smart for his age. The Detective Boys also very much like Sango; they believe that he is a nice and kind man, unlike his twin brother, Jugo.[16]