Our data on the two SNPs in a larger group of
informative (heterozygous) women did not confirm the
initial hypothesis of allele-specific amplification for the
Ala1170Pro SNP, neither was there any clear indication
of preferential amplification of one of the Ile655Val alleles
(Table 3 and Fig. 4). A modest proportion (15%
and 18%) of the HER2-positive cases in our population
retained their heterozygosity for the two variants. This is
in accordance with the previous observation regarding
the Ile655Val SNP