inhibitors in order to enhance the concentration of acetylcholine
(ACh) in the synaptic cleft (Wilkinson et al., 2004). Natural products
might slow the progression of AD because they can simultaneously
protect neurons from oxidative stress (Ramassamy, 2006) and act as
cholinesterases inhibitors (Hostettmann et al., 2006).
The production of phytochemicals is affected by environmental
and physiological conditions and their chemical synthesis is complex due to their structures and specific stereo-chemical characteristics (Smetanska, 2008). Biotechnological approaches, particularly
plant tissue cultures, are found to have significant potential for the
production of high-value phytochemicals. In vitro propagation
methods allow the selective, rapid and effective production of secondary metabolites with no seasonal constraints and independent
of geographical and soil conditions.