In contrast to conventional extraction methods FMAATPE greatly improved the extraction yield of alkaloids under the present of ammonium sulfate. As adding the salt in the mixture ethanol-water, an ATPS could be formed,i.e. a rich-ethanol top phase and a rich-salt bottom phase. Under the action of microwave field, ATPE processes would be intensifiedincluding extraction and demixing, allowing alkaloids to the topphase while leaving impurities in the bottom phase