Adequate dietary intake has been recognized as one of the key factors in maintaining good health, and thereby fostering the quality of life, especially in older adults (i.e. > 65 years of age). It is known, however, that food intake changes with advancing age. Whereas food intake is determined by a complex interplay of factors, older adults rank a food's taste as significantly more important than other factors (e.g., biological, economic, physical, and psychosocial factors) (Krondl et al., 1982) compared to young adults. Notwithstanding the relevance of adequate food intake, there is a lack of knowledge on the specific mechanisms underlying age-related changes in taste perception. The aim of the current study was to investigate the neural substrates of taste perception in young and older adults, by manipulating taste quality and taste concentration.