Systemic lupus erythematosus (SLE) is a chronic multisystem inflammatory rheumatic disease that may cause diverse symptoms, such as fatigue, joint pain, rashes, seizures, edema, and chest pain. 1 2 SLE has a predilection for women, particularly during the prime childbearing age of 15 to 35 years. A wide variety of autoantibodies, including antinuclear antibodies (ANAs), are the most characteristic laboratory finding in SLE. SLE can damage many organ systems, notably the kidneys, lungs, heart, and brain, and may result in severe disability and even death.