TOXIC HEPATITIS
The liver gets more toxic injury than any other organ. This is because it directly receives all the portal
blood (which comes from the intestine) and so is exposed to all ingested substances. Consequently any
toxin which is ingested will hit the liver first. Also, the liver contains an enzyme system, cytochrome P-
450, a major enzyme organization involved in drug metabolism. As drugs or other ingested substances get
metabolized, even if they weren’t toxic to begin with, sometimes the metabolites that are created by the
liver enzymes, turn out to be toxic and kill the liver cells.