The recommendation that can be made to anti-Ro/SSA and anti-La/SSB antibody positive mothers is that serial echocardiography and obstetric ultrasonography should be performed starting from early second trimester. To the pregnant women at high risk such as women with previously affected newborns, it seems necessary to perform weekly monitoring beginning from early second period of gestation and biweekly monitoring between 24-36 weeks. This is crucial for earlier detection of fetal abnormalities, such as premature atrial contractions or moderate pericardial effusions that might precede complete atrioventricular block, ventricular dilatation, mitral valve regurgitation and disrupted cardiac functions (decreased ejection fraction and fractional shortening) that might give us a chance for successful management.Finally, generally accepted management of affected pregnancies is to initiate dexamethasone/betamethasone and/or IVIG therapy just after diagnosis of fetal AV block and to use maternal sympathomimetic for fetal ventricular rates