9 Conclusion
While considerable performance-based evidence exists for the concurrent interference effect,limited data are available regarding the molecular factors responsible and the role of specific training variables in this phenomenon.The majority of current molecular data suggests that endurance exercise does not compromise early anabolic responses to resistance exercise,consequently providing little mechanistic insight into the interference effect seen following long-term concurrent training. However,findings from existing research are complicated by the multitude of potential concurrent training variables and the numerous independent factors capable of influencing acute molecular responses to exercise in human skeletal muscle. Thus,there is substantial difficulty in deducing practical training recommendations from existing research for minimizing interference between concurrent resistance and endurance exercise. Moreover,whilst considerable advances have been made with regards to our understanding of the molecular factors mediating training adaptation in skeletal muscle,these complex processes are incompletely resolved.Observations that anabolic signalling responses to exercise are not always directly coupled to protein synthesis, and that these acute responses are not necessarily predictive of chronic training adaptations,concurrent training represent significant limitations to acute-based concurrent training studies. The possibility remains,therefore,that solely utilising early molecular responses to concurrent exercise to extrapolate any putative chronic interference effect may provide limited insight into factors mediating interference following long-term concurrent training.However,further elucidation of the molecular factors mediating the specificity of training adaptation in human skeletal muscle is warranted,which in turn may provide additional mechanistic insight into the concurrent interference phenomenon.Ultimately,improved understanding of the roles of individual concurrent training variable,including within-session exercise order,length of between-mode recovery,and endurance training volume,intensity and modality,in modulating the interference effect is required to guide exercise prescription for simultaneously maximising divergent training adaptations. Future work should aim to further clarify the roles of these training variables in acute and particularly chronic interference in trained individuals to inform practical recommendations for minimising interference between concurrent resistance and endurance exercise.
Acknowledgments No funding was used to assist in the preparation of this review.The authors have no conflicts of interest to declare that are directly relevant to the contents of this review.The authors would like to thank Keith Baar (University of California Davis) for providing insightful comments on drafts of this manuscript
สรุป 9 While considerable performance-based evidence exists for the concurrent interference effect,limited data are available regarding the molecular factors responsible and the role of specific training variables in this phenomenon.The majority of current molecular data suggests that endurance exercise does not compromise early anabolic responses to resistance exercise,consequently providing little mechanistic insight into the interference effect seen following long-term concurrent training. However,findings from existing research are complicated by the multitude of potential concurrent training variables and the numerous independent factors capable of influencing acute molecular responses to exercise in human skeletal muscle. Thus,there is substantial difficulty in deducing practical training recommendations from existing research for minimizing interference between concurrent resistance and endurance exercise. Moreover,whilst considerable advances have been made with regards to our understanding of the molecular factors mediating training adaptation in skeletal muscle,these complex processes are incompletely resolved.Observations that anabolic signalling responses to exercise are not always directly coupled to protein synthesis, and that these acute responses are not necessarily predictive of chronic training adaptations,concurrent training represent significant limitations to acute-based concurrent training studies. The possibility remains,therefore,that solely utilising early molecular responses to concurrent exercise to extrapolate any putative chronic interference effect may provide limited insight into factors mediating interference following long-term concurrent training.However,further elucidation of the molecular factors mediating the specificity of training adaptation in human skeletal muscle is warranted,which in turn may provide additional mechanistic insight into the concurrent interference phenomenon.Ultimately,improved understanding of the roles of individual concurrent training variable,including within-session exercise order,length of between-mode recovery,and endurance training volume,intensity and modality,in modulating the interference effect is required to guide exercise prescription for simultaneously maximising divergent training adaptations. Future work should aim to further clarify the roles of these training variables in acute and particularly chronic interference in trained individuals to inform practical recommendations for minimising interference between concurrent resistance and endurance exercise.ตอบไม่มีเงินทุนใช้เพื่อช่วยในการจัดทำบทความนี้ผู้เขียนมีประโยชน์ไม่ขัดแย้งกับประกาศที่จะเกี่ยวข้องโดยตรงกับเนื้อหาของบทความนี้ผู้เขียนอยากจะขอบคุณ Keith Baar (มหาวิทยาลัยแคลิฟอร์เนีย Davis) ให้เห็นลึกซึ้งในร่างฉบับนี้
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