worldwide. Infection of this bacterium causes disease in different body organs and easily spreads in the hospital. The emergence and spread of methicillin-resistant and Vancomycine- intermediate S.aureus (VISA) isolates have increased their importance. Understanding the epide- miology and distribution of this bacterium in the com- munity as well as hospitals is necessary to determine its source, to restrict its spread especially in hospital settings. Finding a suitable marker for this purpose has been considered for many years and different methods have been used. Phage typing is one of the oldest meth- ods, which has been declined in the recent years because of its technical problems and the nature of its usage, and instead, molecular methods on the basis of coagulase