When aquarium tanks containing rainbow trout, which had
been reared in darkness on the vitamin D-free diet for 2 years, were
inadvertently exposed for 24 h to 60 W incandescent light, the
trout rapidly became moribund and died. Because it had been
shown that the hepatic 1-hydroxylase of these vitamin D-deficient
fish was very active and that feeding dietary cholecalciferol led to
hypercalcemia, it was postulated that exposure to visible light had
in some way induced the formation of vitamin D in skin which
resulted in a lethal overproduction of 1,25(OH)2D3 and consequent
fatal hypercalcemia. HPLC analysis of lipid extracts from the skin of
a number of species obtained from a
fish market, demonstrated the
presence not only of 7-dehydrocholesterol but also measurable
quantities of cholecalciferol (Table 2). Rainbow trout and Atlantic
salmon had higher levels of 7-dehydrocholesterol in skin than
When aquarium tanks containing rainbow trout, which hadbeen reared in darkness on the vitamin D-free diet for 2 years, wereinadvertently exposed for 24 h to 60 W incandescent light, thetrout rapidly became moribund and died. Because it had beenshown that the hepatic 1-hydroxylase of these vitamin D-deficientfish was very active and that feeding dietary cholecalciferol led tohypercalcemia, it was postulated that exposure to visible light hadin some way induced the formation of vitamin D in skin whichresulted in a lethal overproduction of 1,25(OH)2D3 and consequentfatal hypercalcemia. HPLC analysis of lipid extracts from the skin ofa number of species obtained from afish market, demonstrated thepresence not only of 7-dehydrocholesterol but also measurablequantities of cholecalciferol (Table 2). Rainbow trout and Atlanticsalmon had higher levels of 7-dehydrocholesterol in skin than
การแปล กรุณารอสักครู่..

When aquarium tanks containing rainbow trout, which had
been reared in darkness on the vitamin D-free diet for 2 years, were
inadvertently exposed for 24 h to 60 W incandescent light, the
trout rapidly became moribund and died. Because it had been
shown that the hepatic 1-hydroxylase of these vitamin D-deficient
fish was very active and that feeding dietary cholecalciferol led to
hypercalcemia, it was postulated that exposure to visible light had
in some way induced the formation of vitamin D in skin which
resulted in a lethal overproduction of 1,25(OH)2D3 and consequent
fatal hypercalcemia. HPLC analysis of lipid extracts from the skin of
a number of species obtained from a
fish market, demonstrated the
presence not only of 7-dehydrocholesterol but also measurable
quantities of cholecalciferol (Table 2). Rainbow trout and Atlantic
salmon had higher levels of 7-dehydrocholesterol in skin than
การแปล กรุณารอสักครู่..
