M a ( | Γ = , ) b a γ γ + + γ γ b a + +b a γ γ + b . 0 1 2 3 4
2
5
2
If I is known, Г can be easily solved using the multiple linear
regression method. Moving Yab P, to the right side of the
equation (3), we have
Y Y M a b ab, , O ab P = + ( | Γ ε , ) + .
Since Yab P, is a random term itself, its distribution will be
estimated in the first stage and then be incorporated in
the equation (3) to estimate parameters of the response surface
model. In this way, the variance of the response surface
model parameters will include the variance of Yab O, and the
variance of Yab P, .