When we compared the allele frequency of the patients with
paranoid schizophrenia with that of the healthy control subjects,
we found several alleles that showed high chi-square
values, such as HLA-A*03 (50% and 14%, respectively),
A*11 (32% and 14%, respectively), B*07 (22% and 6%,
respectively), and B*13 (14% and 4%, respectively). In particular,
the A*03 frequency (÷2 = 56.25, P < 0.01) was highly
statistically significant. Conversely, alleles like A*02 (12%
and 28%, respectively) and B*4001 (0% and 8%, respectively)
showed significant values in the control subjects.
When we compared the allele frequency of the patients withparanoid schizophrenia with that of the healthy control subjects,we found several alleles that showed high chi-squarevalues, such as HLA-A*03 (50% and 14%, respectively),A*11 (32% and 14%, respectively), B*07 (22% and 6%,respectively), and B*13 (14% and 4%, respectively). In particular,the A*03 frequency (÷2 = 56.25, P < 0.01) was highlystatistically significant. Conversely, alleles like A*02 (12%and 28%, respectively) and B*4001 (0% and 8%, respectively)showed significant values in the control subjects.
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