Treatment of ESFT consists of two major components: systemic chemotherapy and local control. These two components are carried out in three phases: (1) induction chemotherapy, the goal of which is to achieve rapid initial cytoreduction and facilitate local control; (2) local control using surgery, radiation therapy, or both, usually after 10 to 12 weeks of induction chemotherapy; and (3) continuation therapy, which consists of chemotherapeutic regimens similar to those used for induction