Abstract
This study describes cognitive functioning and its relation to psychiatric and substance use
severity among adults with long duration methamphetamine (MA) use careers. Study participants
(N=405) completed a battery of tests from the Automated Neuropsychological Assessment
Metrics (ANAM), examining cognitive accuracy, processing speed and efficiency. Multivariate
analyses indicate lower accuracy but faster speed on tests of learning and spatial and delayed
memory were correlated with more days of past-month MA use. Lifetime months of MA use was
not related to cognitive functioning. Poorer cognitive efficiency was related to other problems
including crack/cocaine use, depressive symptomatology and poorer emotional state.