CONCLUSION
In conclusion, IA-HA can be a cost-effective
treatment compared to no treatment and also
to conventional care. The comparison of
cost-effectiveness across available HA brands
demonstrated that Euflexxa had the lowest
cost–utility ratio of all investigated HA
products. To validate these findings, additional
clinical trials which include all components of
the WOMAC should be conducted to provide
more thorough data for the derivation of utility
scores.