This process increases the levels of the vasoconstrictor endothelin-1,
which decreases the duodenal mucosal flow and causes tissue ischaemia and hypoxia
[42]. Our results show that pre-treatment with b-myrcene inhibited the cysteamine-induced duodenal lesion.
This protective action
of b-myrcene was accompanied
by significant increases in GSH and a decrease in the MPO level