Tagging gold nanoparticles with snake venom components has been found to increase their uptake by tumor cells[11]. Also silica nanoparticles tagged with snake venom components are observed to act specifically on tumor cells without affecting normal cells[12]. Novel snake venom delivery system with clinical applications to suppress tumors such as intravenous liposomal delivery, recombinant adenovirus carrying snake venom cystatin gene has been described in the literature[6]. Innovative research is required to discover novel, effective therapeutic anticancer agents from snake venoms in oral cancer patients. This promising area of research may bring hope, smile, comfort and cure to these group of cancer patients.