3. Results
3.1. Development of HPOX nanoparticles
As shown in Scheme 1, HPOX was synthesized from a simple
one-step reaction of oxalyl chloride with diols, 0.8 equivalent of
cyclohexanedimethanol and 0.2 equivalent of HBA. HPOX
prepared in this study possesses both aromatic and aliphatic
peroxalate esters and has hydrophobicity sufficient for nanoparticle
formulation by a single emulsion method