Systemic inflammatory response syndrome
(SIRS) is a collection of signs that
the body is reacting to a range of injuries
or illnesses (Box 2), and is not specific to
infection. The body may respond by
raising the heart or respiratory rate to
increase the amount of oxygen – by
altering body temperature or increasing
white cell production – to overcome infection.
Raised blood sugars and new confusion
or an altered mental state may be early
signs of metabolic stress or hypoxia (Survive
Sepsis Organisation, 2009). Although pathways, leading to vasodilatation, vessel
leakage and increased metabolic demands.
This effect increases oxygen demand
which, combined with intravascular losses,
causes hypoperfusion and ischaemia at cellular
levels (Porth, 2005). At this stage, there
will be signs of severe sepsis and evidence of
organ dysfunction away from the primary
source of infection (Box 3).
Systemic inflammatory response syndrome(SIRS) is a collection of signs thatthe body is reacting to a range of injuriesor illnesses (Box 2), and is not specific toinfection. The body may respond byraising the heart or respiratory rate toincrease the amount of oxygen – byaltering body temperature or increasingwhite cell production – to overcome infection.Raised blood sugars and new confusionor an altered mental state may be earlysigns of metabolic stress or hypoxia (SurviveSepsis Organisation, 2009). Although pathways, leading to vasodilatation, vesselleakage and increased metabolic demands.This effect increases oxygen demandwhich, combined with intravascular losses,causes hypoperfusion and ischaemia at cellularlevels (Porth, 2005). At this stage, therewill be signs of severe sepsis and evidence oforgan dysfunction away from the primarysource of infection (Box 3).
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