Lower Bad Cholesterol. Drinking orange juice regularly is thought to decrease levels of low-density lipoprotein, or LDL, cholesterol. LDL cholesterol is commonly known as the “bad” cholesterol and it collects in your arteries and blood vessels, causing heart problems, cardiovascular issues, and problems with healthy blood and blood oxygen flow. The mechanism in drinking orange juice that is behind the improvement in LDL cholesterol levels is still unknown. More studies and clinical trials will need to be performed in order to hammer this out as concrete fact.