The aim of this study was to investigate whether
nutritional supplementation can attenuate central fatigue
and reduce performance decrements under conditions
of environmental stress (simulated heat and hypoxia).
Although these conditions are uncommon, they provide
an opportunity to observe the potentially beneficial effects
of nutritional manipulations under standardized conditions.
Nutritional supplementation, in combination with
assessing markers of central fatigue (e.g., muscle recruitment,
central drive), will clarify the viability of invoking
changes in neurotransmitter concentration in relation to
central fatigue. We hypothesized that central fatigue and
decrements in intermittent exercise performance induced
by environmental stress would be attenuated by targeted
nutritional supplementation strategies using a combination
of both caffeine and EAAs.