Although the composition of PHAs was determined by Lemoigne in 1927, interest in PHAs only started to increase in 1958.
That was the year when Macrae and Wilkinson (1958) observed
that Bacillus megaterium stored a homopolymer especially swiftly
when the glucose-to-nitrogen source ratio of the mediumwas high.
This homopolymer turned out to be poly-3-hydroxybutyrate
[P(3HB)], nowadays the most commonly known and widely
recognized polymer. Since 1958, knowledge about PHAs has greatly
increased. These biopolymers are accumulated by both Gram positive
and Gram negative bacteria, cyanobacteria and even Achaea
(Chee et al., 2010b). Hundreds of bacterial species that can synthesize
PHAs have been counted, and the number is still increasing.
Although the composition of PHAs was determined by Lemoigne in 1927, interest in PHAs only started to increase in 1958.That was the year when Macrae and Wilkinson (1958) observedthat Bacillus megaterium stored a homopolymer especially swiftlywhen the glucose-to-nitrogen source ratio of the mediumwas high.This homopolymer turned out to be poly-3-hydroxybutyrate[P(3HB)], nowadays the most commonly known and widelyrecognized polymer. Since 1958, knowledge about PHAs has greatlyincreased. These biopolymers are accumulated by both Gram positiveand Gram negative bacteria, cyanobacteria and even Achaea(Chee et al., 2010b). Hundreds of bacterial species that can synthesizePHAs have been counted, and the number is still increasing.
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