(0.5 h) was down-regulated in both groups (Fig. 4A). The expression levels in the controls were recovered to or higher than the initial transcript levels (0 h) at later time points. However, the expression levels in the treatment groups never returned to the initial levels (0 h). Additionally, the expression of BCG1 and PKA1 in the control was lower than the initial levels at the final time point, while that of CHS2 and TRE1 was much higher than the initial levels. The expression level of PKA1 was gradually down-regulated by treatment, while a slight reduction was detected in response to the control.