Schizophrenia Patients Not on Antipsychotic Medications: Two Factors of Importance As with other disorders, all schizophrenia patients are not alike. The view of “one treatment fits all” is not consonant with the current data or with clinical experience (Jobe and Harrow, 2005). Some patients have better internal resources, and there are other potential differences in personality style and attitudinal approaches. A number of researchers have pointed out the value of exploring predictors to identify schizophrenia patients who might function adequately with- out antipsychotics. Our data indicate 2 different types of factors that facilitate the better functioning of the patients with schizophrenia who were not on antipsychotics at the 15-year follow-ups. The first set of factors concerns a trend for schizophre- nia patients with favorable scores on the prognostic indices assessed years earlier (at index hospitalization), indicating their potential for better prognoses and better clinical courses, to not be on any antipsychotics many years later.