The physical profile comprising the sample average mass of 17 seized capsules was confronted with authentic samples: 06 fenproporex hydrochloride capsules 25 mg (Desobesi-M1, AChE) and 04 capsules hydrochloride monohydrate sibutramine 10 mg (Saciette1). The mass (mg) was used as a variable in the study. Measurements were performed on an analytical balance (Mettler Toledo XP205, Brazil). Physical aspects of the internal contents of the capsules were also the objects of analysis.