President Palmer is seeking re-election against Senator John Keeler, but his campaign turns sour after one of his major backers, Alan Milliken, discovers that Palmer’s brother, Wayne, has been sleeping with Julia Milliken. Palmer's campaign suffers a major blow when revelations come out about his girlfriend and personal physician Anne Packard. The president turns to his ex-wife Sherry to deal with Milliken. She takes it all a step too far as she kills Milliken by not allowing him his medication, which he needs to stay alive. Despite David Palmer's best cover-up efforts, Keeler uses it as leverage in the campaign. Towards the end of the day, Julia kills Sherry before taking her own life and Palmer decides not to seek re-election.