The n-hexane-soluble extract (291.2 g) was chromatographed over silica gel column chromatography (CC) (70–230 mesh, ϕ 7.4 × 55 cm) as stationary phase with a n-hexane-EtOAc gradient (from 1:0 to 0:1 v/v) as mobile phase to afford 17 pooled fractions (H1–H17).