Bradykinin has multiple roles in the function of our bodies. Which of the following is NOT a characteristic of bradykinin?
a. Decreases blood pressure
b. Involved in pain mechanism
c. Dilates blood vessels
d. Raises blood pressure
Explanation: Bradykinin is a peptide (amino acid chain) that acts like a histamine in that it causes arterior dilation. This will effectively lower blood pressure NOT raise it. The lifecycle of Bradykinin is extended by a class of drugs called ACE (angiotensin-converting) inhibitors (used to treat hypertension) which allows for a greater accumulation within the body. Bradykinin then attaches to pain receptors within the body which increases pain messages to the central nervous system. This is why a client on ACE inhibitors may demonstrate a lower pain tolerance.